CARDIOPROTECTIVE EFFECTS OF CURCUMIN AGAINST DIABETES AND NICOTINE-COMBINED OXIDATIVE STRESS
نویسندگان
چکیده
منابع مشابه
Renoprotective effect of curcumin against the combined oxidative stress of diabetes and nicotine in rats
The progression of diabetic nephropathy (DN) is accelerated by smoking. The current study investigated the ability of curcumin to protect the kidneys against damage from oxidative stress induced by diabetes mellitus (DM) and nicotine (NC). A total of 24 male Wistar rats were divided into four groups of six rats each. DM was induced by a single intraperitoneal injection of streptozotocin 60 mg/k...
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BACKGROUND Recent reports suggested the involvement of oxidative stress- and endoplasmic reticulum stress (ERS)-associated pathways in the progression of ischemia/reperfusion (I/R) injury. Notoginsenoside R1 (NGR1) is a novel saponin isolated from P. notoginseng, which has a history of prevention and treatment of cardiovascular diseases. OBJECTIVE We aimed to examine the cardioprotective effe...
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Background: The present study was conducted to evaluate the effect of curcumin as a flavonoid antioxidant on serum lipid profile, oxidative stress, and blood glucose in experimental models of type 2 diabetes (DM2). Methods: Subcutaneous daily injection of dexamethasone (5 mg/kg/day) for a month was performed to induce DM2. For this purpose, 28 adult male Wistar rats were divided into four group...
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Background. The major side effect of cisplatin, used in some tumours, is nephrotoxicity. Reactive oxygen species and oxidative damage are the most important factors in cisplatin-induced acute renal failure. The main purpose of this study is to investigate the protective effects of crocin against cisplatin-induced acute renal failure and oxidative stress in rat. Methods. In this study, animal...
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ژورنال
عنوان ژورنال: African Journal of Traditional, Complementary and Alternative medicines
سال: 2017
ISSN: 0189-6016,2505-0044
DOI: 10.21010/ajtcam.v14i6.7